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1

Coreceptor Scanning by the T Cell Receptor Provides a Mechanism for T Cell Tolerance

Stepanek, Ondrej, Prabhakar, Arvind S., Osswald, Celine, King, Carolyn G., Bulek, Anna, Naeher, Dieter, Beaufils-Hugot, Marina, Abanto, Michael L., Galati, Virginie, Hausmann, Barbara, Lang, Rosemarie

Journal:

Year:

2014

Language:

english

File:

PDF, 3.09 MB

english, 2014

2

Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity

Israel, Laura, Wang, Ying, Bulek, Katarzyna, Della Mina, Erika, Zhang, Zhao, Pedergnana, Vincent, Chrabieh, Maya, Lemmens, Nicole A., Sancho-Shimizu, Vanessa, Descatoire, Marc, Lasseau, Théo, Israelss

Journal:

Year:

2017

Language:

english

File:

PDF, 3.53 MB

english, 2017

3

TRAF Regulation of IL-17 Cytokine Signaling

Swaidani, Shadi, Liu, Caini, Zhao, Junjie, Bulek, Katarzyna, Li, Xiaoxia

Journal:

Frontiers in Immunology

Year:

2019

Language:

english

File:

PDF, 466 KB

english, 2019

4

The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90

Wang, Chenhui, Wu, Ling, Bulek, Katarzyna, Martin, Bradley N, Zepp, Jarod A, Kang, Zizhen, Liu, Caini, Herjan, Tomasz, Misra, Saurav, Carman, Julie A, Gao, Ji, Dongre, Ashok, Han, Shujie, Bunting, Kev

Journal:

Nature Immunology

Year:

2012

Language:

english

File:

PDF, 1.38 MB

english, 2012

5

Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope

Cole, David K., Fuller, Anna, Dolton, Garry, Zervoudi, Efthalia, Legut, Mateusz, Miles, Kim, Blanchfield, Lori, Madura, Florian, Holland, Christopher J., Bulek, Anna M., Bridgeman, John S., Miles, Joh

Journal:

Frontiers in Immunology

Year:

2017

Language:

english

File:

PDF, 5.29 MB

english, 2017

6

Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes

Bulek, Anna M, Cole, David K, Skowera, Ania, Dolton, Garry, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John J, Gostick, Emma, Price, David A, Drijfhout, Jan W, Knight, Robin R, Huang, Guo

Journal:

Nature Immunology

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

7

Structural basis for ineffective T-cell responses to MHC anchor residue-improved “heteroclitic” peptides

Madura, Florian, Rizkallah, Pierre J., Holland, Christopher J., Fuller, Anna, Bulek, Anna, Godkin, Andrew J., Schauenburg, Andrea J., Cole, David K., Sewell, Andrew K.

Journal:

European Journal of Immunology

Year:

2015

Language:

english

File:

PDF, 642 KB

english, 2015

8

Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)

Sun, Dongxu, Novotny, Michael, Bulek, Katarzyna, Liu, Caini, Li, Xiaoxia, Hamilton, Thomas

Journal:

Nature Immunology

Year:

2011

Language:

english

File:

PDF, 961 KB

english, 2011

9

[IEEE 2009 IEEE/SP 15th Workshop on Statistical Signal Processing (SSP) - Cardiff, United Kingdom (2009.08.31-2009.09.3)] 2009 IEEE/SP 15th Workshop on Statistical Signal Processing - Blind speech separation using fractional order moments

Bulek, Savaskan, Erdol, Nurgun

Year:

2009

Language:

english

File:

PDF, 315 KB

english, 2009

10

TRAF Regulation of IL-17 Cytokine Signaling

Swaidani, Shadi, Liu, Caini, Zhao, Junjie, Bulek, Katarzyna, Li, Xiaoxia

Journal:

Frontiers in Immunology

Year:

2019

File:

PDF, 466 KB

2019

11

The Toll–Interleukin-1 Receptor Member SIGIRR Regulates Colonic Epithelial Homeostasis, Inflammation, and Tumorigenesis

Hui Xiao, Muhammet Fatih Gulen, Jinzhong Qin, Jianhong Yao, Katarzyna Bulek, Danielle Kish, Cengiz Zubeyir Altuntas, David Wald, Caixia Ma, Hang Zhou, Vincent K. Tuohy, Robert L. Fairchild, Carol de l

Journal:

Year:

2007

Language:

english

File:

PDF, 1.88 MB

english, 2007

12

Inactivation of the Enzyme GSK3α by the Kinase IKKi Promotes AKT-mTOR Signaling Pathway that Mediates Interleukin-1-Induced Th17 Cell Maintenance

Gulen, Muhammet F., Bulek, Katarzyna, Xiao, Hui, Yu, Minjia, Gao, Ji, Sun, Lillian, Beurel, Eleonore, Kaidanovich-Beilin, Oksana, Fox, Paul L., DiCorleto, Paul E., Wang, Jian-an, Qin, Jun, Wald, David

Journal:

Year:

2012

Language:

english

File:

PDF, 1.74 MB

english, 2012

13

[IEEE 2009 IEEE 13th Digital Signal Processing Workshop and 5th IEEE Signal Processing Education Workshop - Marco Island, FL, USA (2009.01.4-2009.01.7)] 2009 IEEE 13th Digital Signal Processing Workshop and 5th IEEE Signal Processing Education Workshop - Block Adaptive ICA with a Time Varying Mixing Matrix

Bulek, Savaskan, Erdol, Nurgun

Year:

2009

Language:

english

File:

PDF, 1.00 MB

english, 2009

14

TCR/pMHC Optimized Protein crystallization Screen

Anna M. Bulek, Florian Madura, Anna Fuller, Christopher J. Holland, Andrea J.A. Schauenburg, Andrew K. Sewell, Pierre J. Rizkallah, David K. Cole

Journal:

Journal of Immunological Methods

Year:

2012

Language:

english

File:

PDF, 517 KB

english, 2012

15

T-cell Receptor Specificity Maintained by Altered Thermodynamics

Madura, F., Rizkallah, P. J., Miles, K. M., Holland, C. J., Bulek, A. M., Fuller, A., Schauenburg, A. J. A., Miles, J. J., Liddy, N., Sami, M., Li, Y., Hossain, M., Baker, B. M., Jakobsen, B. K., Sewe

Journal:

Journal of Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 2.54 MB

english, 2013

16

A molecular switch abrogates gp100 TCR-targeting of a human melanoma antigen

Bianchi, Valentina, Bulek, Anna, Fuller, Anna, Lloyd, Angharad, Attaf, Meriem, Rizkallah, Pierre J., Dolton, Garry, Sewell, Andrew K., Cole, David K.

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.44 MB

english, 2016

17

Acoustic Analysis of a Continuous-Flow Left Ventricular Assist Device before and after Suspected Pump Thrombosis

Castagna, F., Pan, S., Garan, A.R., Yuzefpolskaya, M., Takeda, K., Takayama, H., Ross, K., Torres, M., Blum, R.A., Singh, S., Mancini, D.M., Naka, Y., Colombo, P.C., Bulek, S., Topkara, V.K.

Journal:

The Journal of Heart and Lung Transplantation

Year:

2016

Language:

english

File:

PDF, 156 KB

english, 2016

18

In Silico and Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility

Holland, Christopher J., MacLachlan, Bruce J., Bianchi, Valentina, Hesketh, Sophie J., Morgan, Richard, Vickery, Owen, Bulek, Anna M., Fuller, Anna, Godkin, Andrew, Sewell, Andrew K., Rizkallah, Pierr

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 1.64 MB

english, 2018

19

Epithelial Cell-Specific Act1 Adaptor Mediates Interleukin-25-Dependent Helminth Expulsion through Expansion of Lin−c-Kit+ Innate Cell Population

Zizhen Kang, Shadi Swaidani, Weiguo Yin, Chenhui Wang, Jillian L. Barlow, Muhammet Fatih Gulen, Katarzyna Bulek, Jeong-su Do, Mark Aronica, Andrew N.J. McKenzie, Booki Min, Xiaoxia Li

Journal:

Year:

2012

Language:

english

File:

PDF, 1.57 MB

english, 2012

20

Human -Cell Killing by Autoreactive Preproinsulin-Specific CD8 T Cells Is Predominantly Granule-Mediated With the Potency Dependent Upon T-Cell Receptor Avidity

Knight, R. R., Kronenberg, D., Zhao, M., Huang, G. C., Eichmann, M., Bulek, A., Wooldridge, L., Cole, D. K., Sewell, A. K., Peakman, M., Skowera, A.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.40 MB

english, 2013

21

T-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex Interactions

Cole, D. K., Miles, K. M., Madura, F., Holland, C. J., Schauenburg, A. J. A., Godkin, A. J., Bulek, A. M., Fuller, A., Akpovwa, H. J. E., Pymm, P. G., Liddy, N., Sami, M., Li, Y., Rizkallah, P. J., Ja

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 4.08 MB

english, 2014

22

[IEEE 2010 44th Asilomar Conference on Signals, Systems and Computers - Pacific Grove, CA, USA (2010.11.7-2010.11.10)] 2010 Conference Record of the Forty Fourth Asilomar Conference on Signals, Systems and Computers - Exploring sensitivity of joint diagonalization in convolutive blind source separation

Bulek, Savaskan, Erdol, Nurgun

Year:

2010

Language:

english

File:

PDF, 311 KB

english, 2010

23

Structural Mechanism Underpinning Cross-reactivity of a CD8 + T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase

Cole, David K., van den Berg, Hugo A., Lloyd, Angharad, Crowther, Michael D., Beck, Konrad, Ekeruche-Makinde, Julia, Miles, John J., Bulek, Anna M., Dolton, Garry, Schauenburg, Andrea J., Wall, Aaron,

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 4.45 MB

english, 2017

24

SIGIRR, a negative regulator of colon tumorigenesis

Junjie Zhao, Jarod Zepp, Katarzyna Bulek, Xiaoxia Li

Journal:

Drug Discovery Today: Disease Mechanisms

Year:

2011

Language:

english

File:

PDF, 280 KB

english, 2011

25

T Cell-Derived Act1 Is Necessary for IL-25-Mediated Th2 Responses and Allergic Airway Inflammation

Swaidani, S., Bulek, K., Kang, Z., Gulen, M. F., Liu, C., Yin, W., Abbadi, A., Aronica, M., Li, X.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 1.92 MB

english, 2011

26

HuR Is Required for IL-17-Induced Act1-Mediated CXCL1 and CXCL5 mRNA Stabilization

Herjan, T., Yao, P., Qian, W., Li, X., Liu, C., Bulek, K., Sun, D., Yang, W.-P., Zhu, J., He, A., Carman, J. A., Erzurum, S. C., Lipshitz, H. D., Fox, P. L., Hamilton, T. A., Li, X.

Journal:

The Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 1.20 MB

english, 2013

27

272

Wang, Chenhui, Wu, Ling, Bulek, Katarzyna, Martin, Bradley N., Zepp, Jarod A., Kang, Zizhen, Liu, Caini, Herjan, Tomasz, Misra, Saurav, Carman, Julie A., Gao, Ji, Dongre, Ashok, Han, Shujie, Bunting,

Journal:

Year:

2013

Language:

english

File:

PDF, 42 KB

english, 2013

28

The Essential Role of Single Ig IL-1 Receptor-Related Molecule/Toll IL-1R8 in Regulation of Th2 Immune Response

Bulek, K., Swaidani, S., Qin, J., Lu, Y., Gulen, M. F., Herjan, T., Min, B., Kastelein, R. A., Aronica, M., Kosz-Vnenchak, M., Li, X.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 876 KB

english, 2009

29

POLLUTED ASSETS

Wang, Chenhui, Wu, Ling, Bulek, Katarzyna, Martin, Bradley N., Zepp, Jarod A., Kang, Zizhen, Liu, Caini, Herjan, Tomasz, Misra, Saurav, Carman, Julie A., Gao, Ji, Dongre, Ashok, Han, Shujie, Bunting,

Journal:

Year:

1963

Language:

english

File:

PDF, 180 KB

english, 1963

30

SY-16 The critical role of epithelial-derived act1 in IL-17- and IL-25-mediated pulmonary inflammation

Shadi Swaidani, Katarzyna Bulek, Zizhen Kang, Caini Liu, Yi Lu, Mark Aronica, Xiaoxia Li

Journal:

Year:

2008

Language:

english

File:

PDF, 121 KB

english, 2008

31

Peptide length determines the outcome of TCR/peptide-MHCI engagement

Ekeruche-Makinde, J., Miles, J. J., van den Berg, H. A., Skowera, A., Cole, D. K., Dolton, G., Schauenburg, A. J. A., Tan, M. P., Pentier, J. M., Llewellyn-Lacey, S., Miles, K. M., Bulek, A. M., Cleme

Journal:

Year:

2013

Language:

english

File:

PDF, 1.21 MB

english, 2013

32

IL-27, targeting antigen-presenting cells, promotes Th17 differentiation and colitis in mice

Visperas, A, Do, J S, Bulek, K, Li, X, Min, B

Journal:

Mucosal Immunology

Year:

2014

Language:

english

File:

PDF, 1.77 MB

english, 2014

33

Interleukin-1 Receptor-associated Kinase 2 Is Critical for Lipopolysaccharide-mediated Post-transcriptional Control

Wan, Y., Xiao, H., Affolter, J., Kim, T. W., Bulek, K., Chaudhuri, S., Carlson, D., Hamilton, T., Mazumder, B., Stark, G. R., Thomas, J., Li, X.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 1.14 MB

english, 2009

34

The Critical Role of Epithelial-Derived Act1 in IL-17- and IL-25-Mediated Pulmonary Inflammation

Swaidani, S., Bulek, K., Kang, Z., Liu, C., Lu, Y., Yin, W., Aronica, M., Li, X.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 585 KB

english, 2009

35

TCR‐induced alteration of primary MHC peptide anchor residue

Madura, Florian, Rizkallah, Pierre J., Legut, Mateusz, Holland, Christopher J., Fuller, Anna, Bulek, Anna, Schauenburg, Andrea J., Trimby, Andrew, Hopkins, Jade R., Wells, Stephen, Godkin, Andrew, Mil

Journal:

European Journal of Immunology

Year:

2019

File:

PDF, 1.72 MB

2019

36

Epithelium: the interplay between innate and Th2 immunity

Bulek, Katarzyna, Swaidani, Shadi, Aronica, Mark, Li, Xiaoxia

Journal:

Immunology & Cell Biology

Year:

2010

Language:

english

File:

PDF, 816 KB

english, 2010

37

CS10-3. IKKi is required for interleukin 17-dependent signaling associated with neutrophilia and pulmonary inflammation

Katarzyna Bulek, Caini Liu, Shadi Swaidani, Liwen Wang, Richard C. Page, Muhammet F. Gulen, Tomasz Herjan, Amina Abbadi, Wen Qian, Dongxu Sun, Mark Lauer, Vincent Hascall, Saurav Misra, Mark Chance, M

Journal:

Year:

2011

Language:

english

File:

PDF, 135 KB

english, 2011

38

296

Zepp, Jarod A., Liu, Caini, Gulen, Muhammet F., Zhao, Junjie, Gu, Chunfang, Bulek, Katarzyna, Li, Xiaoxia

Journal:

Year:

2013

Language:

english

File:

PDF, 42 KB

english, 2013

39

IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs

Zhou, Hao, Bulek, Katarzyna, Li, Xiao, Herjan, Tomasz, Yu, Minjia, Qian, Wen, Wang, Han, Zhou, Gao, Chen, Xing, Yang, Hui, Hong, Lingzi, Zhao, Junjie, Qin, Luke, Fukuda, Koichi, Flotho, Annette, Gao,

Journal:

Year:

2017

Language:

english

File:

PDF, 5.97 MB

english, 2017

40

A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity

Kim, T. W., Staschke, K., Bulek, K., Yao, J., Peters, K., Oh, K.-H., Vandenburg, Y., Xiao, H., Qian, W., Hamilton, T., Min, B., Sen, G., Gilmour, R., Li, X.

Journal:

Journal of Experimental Medicine

Year:

2007

Language:

english

File:

PDF, 2.50 MB

english, 2007

41

IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression

Wang, Chenhui, Zhang, Cun-Jin, Martin, Bradley N., Bulek, Katarzyna, Kang, Zizhen, Zhao, Junjie, Bian, Guanglin, Carman, Julie A., Gao, Ji, Dongre, Ashok, Xue, Haibo, Miller, Stephen D., Qian, Youcun,

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 2.93 MB

english, 2017

42

IL-17A–Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis

Zepp, Jarod A., Zhao, Junjie, Liu, Caini, Bulek, Katazyna, Wu, Ling, Chen, Xing, Hao, Yujun, Wang, Zhenghe, Wang, Xinxin, Ouyang, Wenjun, Kalady, Matthew F., Carman, Julie, Yang, Wen-Pin, Zhu, Jun, Bl

Journal:

The Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 1.89 MB

english, 2017

43

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis

Liao, Yun, Zhao, Junjie, Bulek, Katarzyna, Tang, Fangqiang, Chen, Xing, Cai, Gang, Jia, Shang, Fox, Paul L., Huang, Emina, Pizarro, Theresa T., Kalady, Matthew F., Jackson, Mark W., Bao, Shideng, Sen,

Journal:

Nature Communications

Year:

2020

File:

PDF, 4.13 MB

2020

44

T cell Receptor Alpha Variable 12-2 bias in the immunodominant response to Yellow fever virus

Bovay, Amandine, Zoete, Vincent, Dolton, Garry, Bulek, Anna M., Cole, David K., Rizkallah, Pierre J., Fuller, Anna, Beck, Konrad, Michielin, Olivier, Speiser, Daniel E., Sewell, Andrew K., Fuertes Mar

Journal:

European Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 2.59 MB

english, 2017

45

The Receptor SIGIRR Suppresses Th17 Cell Proliferation via Inhibition of the Interleukin-1 Receptor Pathway and mTOR Kinase Activation

Muhammet F. Gulen, Zizhen Kang, Katarzyna Bulek, Wan Youzhong, Tae Whan Kim, Yi Chen, Cengiz Z. Altuntas, Kristian Sass Bak-Jensen, Mandy J. McGeachy, Jeong-Su Do, Hui Xiao, Greg M. Delgoffe, Booki Mi

Journal:

Year:

2010

Language:

english

File:

PDF, 1.44 MB

english, 2010

46

174 IRAK2 is critical for LPS-mediated post-transcriptional control

Hui Xiao, Youzhong Wan, Tae Whan Kim, Katarzyna Bulek, Sujan Chaudhuri, Barsanjit Mazumder, George R. Stark, James Thomas, Xiaoxia Li

Journal:

Year:

2008

Language:

english

File:

PDF, 46 KB

english, 2008

47

IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production

Zhou, Hao, Yu, Minjia, Fukuda, Koichi, Im, Jinteak, Yao, Peng, Cui, Wei, Bulek, Katarzyna, Zepp, Jarod, Wan, Youzhong, Whan Kim, Tae, Yin, Weiguo, Ma, Victoria, Thomas, James, Gu, Jun, Wang, Jian-an,

Journal:

The EMBO Journal

Year:

2013

Language:

english

File:

PDF, 2.97 MB

english, 2013

48

287 ACT1 is required for IL-25-dependent TH2 responses

Shadi Swaidani, Katarzyna Bulek, Zizhen Kang, Caini Liu, Yi Lu, Mark Aronica, Xiaoxia Li

Journal:

Year:

2008

Language:

english

File:

PDF, 44 KB

english, 2008

49

A Penalty Function Promoting Sparsity Within and Across Groups

Bayram, Ilker, Bulek, Savaskan

Journal:

IEEE Transactions on Signal Processing

Year:

2017

Language:

english

File:

PDF, 1.37 MB

english, 2017

50

[IEEE 2011 Digital Signal Processing and Signal Processing Education Meeting (DSP/SPE) - Sedona, AZ, USA (2011.01.4-2011.01.7)] 2011 Digital Signal Processing and Signal Processing Education Meeting (DSP/SPE) - Effects of cross-spectrum estimation in convolutive blind source separation: A comparative study

Bulek, Savaskan, Erdol, Nurgun

Year:

2011

Language:

english

File:

PDF, 127 KB

english, 2011

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